2026-07-22 · 5 min read
Mercedes-Benz S-Class Tyre Guide Malaysia — W222/W223 Sizes
W222 S350/S400/S500 run 245/45R18 to 255/35R20; W223 S400/S450 use 245/45R19 or 265/40R20. Flagship tyre choice for comfort and wet grip — Michelin PS5, Continental SC7 and Pirelli P7 reviewed.

S-Class runs large, wide tyres: 245/45R18 to 275/40R20 depending on variant and wheel size. Run-flat tyres (MOE) are standard on many S-Class variants — these must not be replaced with standard tyres without also replacing the TPMS sensors and updating the ECU.
Key Tyre Points
- Run-flat (MOE): if original equipment is MOE, replacement must also be MOE — conventional tyres cannot be mixed
- Staggered setup (wider rear): W222 S-Class often has wider rear tyres — check each axle spec before ordering
- Recommended brands: Michelin Pilot Sport 4S, Continental SportContact 6, Pirelli P Zero (all must be MOE variant if car came with run-flats)
- Rotation: front-to-rear if same size. Staggered: no rotation possible — replace axle by axle
